Hims and Hers Health's compounded Wegovy pill offering fuels market jitters

Hims & Hers HIMS.N said it would begin offering compounded versions of Novo Nordisk's NOVOb.CO Wegovy pill at an introductory price of $49 per month.

The company said the offering would be guided by clinical recommendations for personalized treatment, mirroring the approach it had taken with compounded injectable weight-loss drugs.

Shares of Novo and rival Eli Lilly LLY.N dropped after the launch announcement over concerns on how companies will protect margins as lower-cost alternatives emerge.

Below are some reactions to the announcement:

Karen Andersen, analyst at Morningstar

"If Hims is allowed to proceed with this launch, I'm not sure why they won't just launch compounded orforglipron once Lilly receives approval for that (expected in the second quarter), or really any new drug, for that matter. Either the laws protecting branded drugs aren't clear enough, or they aren't being enforced, or both."

"I know one area that Hims focuses on is patients who want to take very low doses of semaglutide. This lessens the production capacity that is required, but for the pill, you need a much higher dose to be effective, even if you have the SNAC technology. So I'm not sure they would have the capacity to be a meaningful player here, assuming they are selling at a dose that is effective."

Michael Cherny, analyst, Leerink Partners

"The compounded semaglutide pill is an extremely logical new product offering given the existing platform within weight loss and expected demand from available oral GLP-1s... there is no reason why Hims shouldn't evaluate these launches for every subsequent weight-loss product as the market continues to evolve, even if the company has not historically focused on tirzepatide."

Christian Moore, HC specialist at Bernstein

"The Reuters report is spooking both companies and investors questioning the legality of this vs the viability of it."

Moore said the timing of the Hims announcement, coming shortly after Novo and Lilly earnings and outlooks isn't ideal, and gives the market yet another thing to worry about.

-Reporting by Mariam Sunny, Christy Santhosh, Mrinalika Roy in Bengaluru; Editing by Shilpi Majumdar/Reuters