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Novartis to buy breast cancer drug candidate from Synnovation

Novartis is set to acquire a promising breast cancer drug candidate from Synnovation Therapeutics in a deal worth up to $3 billion, strengthening its oncology pipeline. The experimental therapy targets HR-positive/HER2-negative breast cancer using a next-generation PI3Kα inhibition approach.

Ludwig Burger/Reuters

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March 20, 2026

Novartis to buy breast cancer drug candidate from Synnovation

FILE PHOTO: The company's logo is seen at a building of Swiss drugmaker Novartis in Rotkreuz, Switzerland, January 29, 2020.

Arnd Wiegmann/Reuters

Novartis NOVN.S said on Friday it agreed to acquire breast cancer drug candidate SNV4818 from Synnovation Therapeutics for $2 billion upfront and up to $1 billion contingent on further development achievements.


The experimental drug belongs to the class of selective PI3Kα inhibitors, a new approach for the treatment of a type of breast cancer known as HR positive/HER2 negative and potentially other solid tumours.

-Ludwig Burger/Reuters

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